Preheat the oven to 400 °F. If using frozen chicken tenders, cook them ahead of time according to the directions on the package. Slice into smaller bite-sized peices and set aside.
Meanwhile, roll out the dough into a 12-inch circle, like you would pizza crust.
Choose one half, and spread buffalo sauce over the dough, leaving a one inch border around the edge. Top the same half with chicken, red onion, and mozzarella cheese.
Fold the other half of the dough over the filling to the opposite edge, forming a half moon shape. Pinch the ends together to seal.
Place calzone on a greased baking sheet and baste the entire top with melted butter. Bake for 20-25 minutes or until top of the calzone is slightly golden.
Remove from the oven, let cool for 5-7 minutes, and slice into strips for serving. Serve with blue cheese.